ProMed Pharma Press Release April 2022

ProMed Pharma announces a preclinical rat study to assess pharmacokinetics of a novel long-acting contraceptive implant

Bioresorbable implant aims to address key unmet needs for
family planning at an affordable price in low and middle
income (LMIC) settings

PLYMOUTH, MINNESOTA, UNITED STATES, April 19, 2022
/EINPresswire.com/ -- ProMed Pharma is pleased to
announce the initiation of preclinical evaluation of a novel
fully resorbable contraceptive implant. The implant,
developed in a project funded by the Bill & Melinda Gates
Foundation, aims to address key unmet needs for family
planning at an affordable price in low and middle income
(LMIC) settings.

Commercially available contraceptive implants, while safe
and highly effective, require removal by trained health care
providers any time the user wants to discontinue the
method, including when pregnancy is desired, or when the
implant reaches the end of its effectiveness. This
requirement imposes a strain on resources in LMIC
settings.

The implant being developed by ProMed is specifically designed to address the needs of LMIC settings.
First, it aims to expand women’s contraceptive options by providing 18 months of contraception by long-term release of levonogestrel. This duration fills the gap between that offered by existing injectables and longer-acting methods such as non-erodible implants.
Second, the implant is fully biodegradable, eliminating the need for women to return to medical clinics for removal at the end of the period of effectiveness.
Finally, the implant, which comprises a levonogestrel-releasing outer sheath surrounding a drug-free polymer core, is designed to retain sufficient mechanical integrity to allow removal if or when desired. Removability is important to respond to women’s needs, such as in cases where pregnancy is desired prior to exhaustion of the contraceptive.

The preclinical evaluation of the implants follows selection of four lead formulations combining levonogestrel with cost-effective, commercially available biopolymers that yield near-linear release without the need of a rate controlling membrane. The preclinical study will evaluate the pharmacokinetics of levonogestrel, establish duration of removability, and track length of biodegradation of the designs. The results will allow further narrowing of formulations for clinical evaluation.

Dr. James Arps, Director of Business Development at ProMed, noted “the implant designs have shown promising mechanical integrity and drug release profiles based on in vitro tests to date and have a form factor which is similar if not superior to other implants on the market.” The study will be carried on for a minimum of 6 months with the option of gathering drug release and polymer degradation data up to 1.5 years.

About ProMed Pharma:

ProMed Pharma specializes in the molding and extrusion of drug-loaded silicones, thermoplastics, and bioresorbable materials, leveraging this expertise to manufacture long-term implants and combination devices under cGMP. Working with both established and early stage companies, we utilize robust manufacturing processes for controlled release of APIs utilizing a variety of materials. From clinical trial materials to commercial products, ProMed supports
pharmaceutical and medical device companies developing controlled release formulations including subcutaneous, orthopedic, cardiovacular, and ophthalmic implants, intravaginal rings, and steroid-eluting combination components. The company has facilities in Plymouth and Maple Grove, Minnesota. Please visit www.promedpharmallc.com for more information.

James Arps
Promed Pharma
+1 763-331-3800
email us here
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DFM Checklist for Medical Manufacturing

Injection molding and other medical manufacturing processes are often complex and peppered with potential pitfalls. Fortunately, nearly all of these potential issues can be resolved with a highly competent design. Achieving the best design the first time around is crucial as there is a lot at stake. If OEMs do not get the design right, product rejection rates will increase, productivity will decline, and a host of other issues will ensue – all negatively impacting the bottom line. Additionally, modifying a product or mold design during the production stage can be very costly – so it is worth the time to get the design phase right.

One approach used in medical manufacturing to ensure the best design is Design for Manufacturing, or DFM. This is the process of designing products for ease of manufacturing as well as creating a better, more cost-effective product. DFM is a vital product development step that looks to simplify and optimize the design to ensure high quality and efficiency during production.

One apThe DFM process should occur early in the design phase of any molding project and should engage key parties including designers, tool fabricators, raw material suppliers, manufacturers, and other stakeholders. The goal is to tap into the experience of each of these experts. The team will scrutinize the current design from many angles with the goal of identifying a more cost-effective solution that maintains excellent quality.

How does the DFM Process Add Value?

Simply stated, OEMs need to ensure the part is as easy to manufacture as possible. This will result in more efficient production, better quality, and lower cycle times. Below are some ways OEMs gain value from the Design for Manufacturing process.

· Save Significant Cost and Time: OEMs are often in a rush to get a new product to market so it is tempting to shorten – or even skip – the DFM process. However, it is important to keep in mind that changes to the design become exponentially more expensive and timely to implement as the product advances through the life cycle. A thorough DFM upfront will allow any optimizations to be made or issues to be resolved before the changes significantly impact the project timeline or budget.

· Optimize Functionality and Aesthetics: tooling for molding projects is often expensive to fabricate and costly to modify; thus, it is imperative to get the tool design right the first time. If the design is off even by a small margin, the product aesthetics and functionality will be altered. The DFM process often includes computer simulations of the design as well as rapid prototyping so the team can fully visualize the product. Oftentimes, these steps yield valuable insights and design optimizations that would have been lost if the DFM process was not performed – resulting in a more functional and aesthetically-pleasing product.

· Confirm Manufacturability: last but certainly not least, the DFM process ensures the part can be manufactured. This may seem obvious but there are many instances of products reaching production only to realize the part cannot actually be manufactured per its current design – costing OEMs valuable time, money, and resources

ProMed’s Approach to DFM

To avoid this situation, OEMS should team up with an experienced medical manufacturing partner, like ProMed, that has DFM expertise. ProMed’s design and manufacturing teams are integrated to allow manufacturability issues to be identified and addressed during the design process instead of after the tooling is fabricated – saving customers significant development time and cost as well as innumerable headaches. At ProMed, we works with our customers throughout the product life cycle, providing a cost-effective solution that meets the customer’s needs.

LSR is a versatile silicone that has a wide range of end-uses from medical devices to consumer goods to electronics to automotive. There are several types of LSR that can be manufactured such as medical, self-lubricating, conductive, flame-retardant, and radio opaque. The type of LSR produced is determined by the additives incorporated during the manufacturing process. Additionally, LSR is available in different grades, namely medical, food, and industrial. Given its versatility, it is not surprising that the worldwide demand for LSR continues to grow.

LSR has excellent properties, such as a low viscosity and low shrink rate, that make it a great choice for silicone injection molding and the manufacturing of complex products and intricate parts. One of the benefits of LSR is that it cures faster than most other rubber materials; additionally, due to the highly automated nature of silicone injection molding and the potential for 24/7 manufacturing, high volumes of LSR products can be produced in a short period of time – adding to its popularity.

A key benefit of LSR’s lower viscosity is that it is easier to mix additives into. Additives that can readily be incorporated into a batch of LSR include colorants, desiccants, barium, and pharmaceuticals such as hormones or steroids. For these reasons, LSR is a great option for medical devices such as combination products. The low viscosity of LSR and the temperatures needed to vulcanize LSR are usually low enough that significant degradation of compounded substances, like Active Pharmaceutical Ingredients (APIs) that are used in combination products, can be avoided.

While LSR has many attractive properties, its biocompatibility is outstanding. LSR has demonstrated superb compatibility with human tissue and body fluids, and is resistant to bacteria growth. Medical grades of LSR are temperature resistance and can easily sterilize, which makes them compatible with various medical devices and accessories such as implantable devices, liquid feeding bottles, dialysis filters, and oxygen mask instruments.

Looking for a proven and reliable medical manufacturing partner for your next silicone injection molding project?

Contact the professionals at ProMed to learn more about our range of medical manufacturing solutions and the various silicone materials we utilize.

DFM Checklist for Medical Manufacturing

There are many factors to consider when designing a molded product for the healthcare sector. Below is an example of a DFM checklist that lists key design consideration for an injection molding project. These are topics that OEMs should discuss with their medical manufacturing partner to ensure each of these items is considered in the product design. This is not a comprehensive list but these are some of the most common design parameters that will help ensure a robust design and a successfully molded product. The DFM checklist for your project can be customized to meet the specifics of your application. Visit our website for more medical manufacturing design considerations regarding material selection and part functionality.

· Simplification:

o Can the product size or geometry be simplified or standardized?

o Can complex features such as undercuts or sharp corners be simplified or removed?

o Are all specified tolerances necessary, and which dimensions/tolerances are critical?

· Part thickness:

o Can the part be made to have a uniform thickness throughout?

o Check for thick areas of the part that could result in sinks and voids

o Check for thin areas of the part that could result non-fill

· Part Draft:

o Does sufficient draft exist? Is draft in the right direction and location for a good parting line?

o If texture is being used, is there enough draft to release the part?

· Gate location:

o Can the gate be located in a thick area of the part?

o Will the gate seal at the right time?

o Are multiple gates needed?

· Material considerations:

o Will the material have flow concerns such as excessive shear?

o If the resin does not flow well, are long or thin flow lengths needed?

o Is the fiber orientation correct?

· Operating conditions to consider:

o Maximum pressure during filling and packing

o Clamp force profile

o Fill pattern – is there a potential for material solidification, voids, or hot spots?

o Temperature profile

o Venting temperature - is there a potential for air traps?

· Defects:

o Consider the potential for flash, weld lines, sink marks, short shots, burn marks, shrinkage, warpage, etc.

· Tooling: potential for tool integrity concerns such as thin steel?

About ProMed

ProMed was founded in 1989 to address an industry need for cleanroom manufacturing of silicone components, specifically those having a medical application. Over time, we broadened our product offerings to include assembly, micro-molding of highly engineered plastics, and combination products. We have garnered a reputation as the world benchmark of implantable silicone components and assemblies – and are one of few companies in the world to provide contract manufacturing of drug-eluting products.

ProMed has expertise in working with the full spectrum of silicones covering a wide range of properties and characteristics. We will assist in your material selection to help ensure all design requirements are met. Our manufacturing facilities and equipment are designed for a single purpose—to mold medical and implantable silicone, combination components, and bio-material grade plastics with uncompromising quality and service. We currently have four divisions that are located within two manufacturing sites. All are certified class 10,000 / ISO Class 7 cleanrooms.

We can identify the right manufacturing solution for any project. We have extensive experience in a wide range of injection molding techniques including:

· Automated Silicone Injection Molding

· Multi-cavity tooling

· Micro molds and micro molding

· Servo-controlled de-molding capabilities

· Insert molds, overmolds, and automation integration

· Transfer molding

· Compression molding

Click here to see why ProMed is your silicone injection molding partner. Contact ProMed today at 763-331-3800 to discuss your next silicone injection molding project.


Common Materials for Silicone Injection Molding

MediSilicone injection molding is a cost-effective manufacturing solution that many OEMs rely on for high-quality, efficient production. This method of manufacturing is very common within the medical sector and has several benefits compared to other molding processes. For example, silicone injection molding is a good choice for a wide range of part sizes, materials, and colors – including highly intricate and complex parts. This method produces products that are virtually identical from part to part which provides excellent brand consistency and part reliability during high volume runs, which is especially crucial for products used in the medical industry. The high reproducibility of silicone injection molding also allows for production to be scaled up to very large volumes, resulting in low costs per unit.

Common Silicones for Injection Molding: LSR and HCR

Silicone elastomers have long been a popular material for silicone injection molding due to their highly desirable mechanical and physical properties. Silicones have excellent durability, chemical inertness, high tensile strength, vast range of available durometers, low toxicity, a wide temperature range, and compatibility with many sterilization methods. Furthermore, silicone is compatible with human tissue and body fluids, has a very low tissue response when implanted, and does not support bacteria growth – making it a perfect option for implants due to its excellent biocompatibility.

Silicone elastomers are primarily available in two forms for medical manufacturing: Liquid Silicone Rubber (LSR) and High Consistency Rubber (HCR). LSR and HCR are both used in medical manufacturing. While HCR and LSR have several similarities, viscosity is a key differentiator and often impacts the decision on which material is utilized for a given silicone injection molding project. The following provides an overview of both elastomers and when each should be utilized.

What is Liquid Silicone Rubber (LSR)?

Liquid Silicone Rubber (LSR) is a platinum-cured elastomer. LSR is a newer silicone technology and starts out as a 2-part liquid that cures into a solid form when mixed. LSR generally comes in buckets and has a longer shelf life than HCR.

LSR is a versatile silicone that has a wide range of end-uses from medical devices to consumer goods to electronics to automotive. There are several types of LSR that can be manufactured such as medical, self-lubricating, conductive, flame-retardant, and radio opaque. The type of LSR produced is determined by the additives incorporated during the manufacturing process. Additionally, LSR is available in different grades, namely medical, food, and industrial. Given its versatility, it is not surprising that the worldwide demand for LSR continues to grow.

LSR has excellent properties, such as a low viscosity and low shrink rate, that make it a great choice for silicone injection molding and the manufacturing of complex products and intricate parts. One of the benefits of LSR is that it cures faster than most other rubber materials; additionally, due to the highly automated nature of silicone injection molding and the potential for 24/7 manufacturing, high volumes of LSR products can be produced in a short period of time – adding to its popularity.

A key benefit of LSR’s lower viscosity is that it is easier to mix additives into. Additives that can readily be incorporated into a batch of LSR include colorants, desiccants, barium, and pharmaceuticals such as hormones or steroids. For these reasons, LSR is a great option for medical devices such as combination products. The low viscosity of LSR and the temperatures needed to vulcanize LSR are usually low enough that significant degradation of compounded substances, like Active Pharmaceutical Ingredients (APIs) that are used in combination products, can be avoided.

While LSR has many attractive properties, its biocompatibility is outstanding. LSR has demonstrated superb compatibility with human tissue and body fluids, and is resistant to bacteria growth. Medical grades of LSR are temperature resistance and can easily sterilize, which makes them compatible with various medical devices and accessories such as implantable devices, liquid feeding bottles, dialysis filters, and oxygen mask instruments.

Looking for a proven and reliable medical manufacturing partner for your next silicone injection molding project?

Contact the professionals at ProMed to learn more about our range of medical manufacturing solutions and the various silicone materials we utilize.

What is High-Consistency Rubber (HCR)?

Another common elastomer for silicone injection molding is High-Consistency Rubber, or HCR. It should be noted that the terms HCR and HTV, which stands for High Temperature Vulcanization, are often used interchangeably and refer to the same silicone material; for the purpose of this article, we will use the acronym HCR.

HCR is a type of silicone elastomer comprised of long polymer chains with a very high molecular weight. It is cured at high temperatures with a platinum catalyst or peroxides. HCR is known for its gummy consistency that is similar to peanut butter, and mostly comes in partially vulcanized sheets.

HCR has many desirable properties such as excellent aging resistance, thermal stability, electrical properties, mechanical strength, elongation, and hardness. For these reasons, HCR is a good material for a broad range of applications within medical manufacturing. Due to its higher viscosity compared to other elastomers such as LSR, HCR is typically processed using compression and transfer molding methods, but is also utilized for silicone injection molding projects.

HCR takes longer to cure than many other molding materials. A longer cure time results in a longer silicone injection molding cycle time. To improve project economics, HCR molds often have a large number of

cavities in order to accommodate the longer cycles and still achieve the desired production volume for each cycle – resulting in a more cost-effective solution on a per unit basis.

Which Silicone is Best for My Injection Molding Project?

Medical device OEMs often face a tough decision: should we use HCR or LSR for our silicone injection molding project? For companies already using HCR to manufacture medical components, it may make sense to continue using this elastomer especially since the initial capital equipment costs have already been made. For new product development, however, LSR is often the best choice given the lower capital costs and labor associated with processing this silicone. Due to its lower cost and versatility with formulations, companies often prefer LSR over HCR – but the decision should be made on a case-by-case basis. This is why it is important to team up with an experienced partner, such as ProMed, who will guide you through the selection process to ensure the right material is chosen for your silicone injection molding project.

About ProMed

ProMed was founded in 1989 to address an industry need for cleanroom manufacturing of silicone components, specifically those having a medical application. Over time, we broadened our product offerings to include assembly, micro-molding of highly engineered plastics, and combination products. We have garnered a reputation as the world benchmark of implantable silicone components and assemblies – and are one of few companies in the world to provide contract manufacturing of drug-eluting products.

ProMed has expertise in working with the full spectrum of silicones covering a wide range of properties and characteristics. We will assist in your material selection to help ensure all design requirements are met. Our manufacturing facilities and equipment are designed for a single purpose—to mold medical and implantable silicone, combination components, and bio-material grade plastics with uncompromising quality and service. We currently have four divisions that are located within two manufacturing sites. All are certified class 10,000 / ISO Class 7 cleanrooms.

We can identify the right manufacturing solution for any project. We have extensive experience in a wide range of injection molding techniques including:

· Automated Silicone Injection Molding

· Multi-cavity tooling

· Micro molds and micro molding

· Servo-controlled de-molding capabilities

· Insert molds, overmolds, and automation integration

· Transfer molding

· Compression molding

Click here to see why ProMed is your silicone injection molding partner. Contact ProMed today at 763-331-3800 to discuss your next silicone injection molding project.


Why Silicone Injection Molding is a Great Choice for Medical Manufacturing

When it comes to medical manufacturing, companies have a variety of methods to choose from ranging from molding to machining to 3D printing.  The following explains why silicone injection molding is a great choice for medical manufacturing – and why it may be the best option for your next project.

Why Medical Manufacturing Prefers Silicones

Silicones have long been a popular material for medical devices due to their durability, wide temperature range, chemical inertness, high tensile strength, vast range of available durometers, low toxicity, and compatibility with many sterilization methods. Furthermore, silicone has a unique molecular structure, namely its silicon-oxygen backbone, that results in several excellent properties that are desirable for medical manufacturing such as:

  • Superior Biocompatibility: medical products often come in contact with the human body – either externally on a patient’s skin or internally as an implant that contacts tissue and fluids. Silicones are compatible with human tissue and body fluids, have a very low tissue response when implanted, and do not support bacteria growth. Additionally, medical-grade silicones, such as Liquid Silicone Rubber (LSR), have undergone stringent purity and biocompatibility testing that make them suitable for short and long-term usage. Simply put, silicones are unmatched in their biocompatibility, making them an excellent option for medical manufacturing.

 

  • Withstands Sterilization: medical grade material must be able to withstand sterilization in order to minimize contaminants and the risk of infections. Devices and products made of medical grade silicone are easily sterilized and resist bacteria growth. In fact, medical grade silicones are often processed in special facilities called cleanrooms that reduce the potential for contamination. For example, all of ProMed’s manufacturing facilities are equipped with certified class 10,000 / ISO Class 7 cleanrooms, demonstrating a strong commitment to quality.

 

  • Superb Stability: silicone is known for its resistance to UV, weather, and other environmental conditions that tend to age materials, leading to a high level of stability and long-life span for silicone products. These characteristics are critical for a number of medical devices such as implantables.

 

  • Broad Temperature Range: compared to other materials, LSR and other silicones have excellent thermal stability. LSR blends are able to withstand high temperatures without deforming or melting. As for low temperatures, LSR maintains its flexibility and does not become brittle and vulnerable to breaking like thermoplastic elastomers.

 

  • Low Viscosity: the low viscosity of LSR makes it a great material for making medical devices via silicone injection molding, since the LSR can easily flow into and completely fill molds with relatively low injection pressures, even those with small, complex, or high-tolerance features. A lower viscosity also makes it easier for manufacturers to mix in additives including colorants, desiccants, barium, and pharmaceuticals such as hormones or steroids. For these reasons, LSR is a great option for medical devices such as combination products.
  • Quick Cure Rate: one of the benefits of silicones, like LSR, is that it cures faster than most other rubber materials – in some cases in only seconds. Additionally, due to the highly automated nature of silicone injection molding and the potential for 24/7 manufacturing, high volumes of medical products can be produced in a short period of time – adding to its popularity.

Looking for a reliable and proven partner for your next medical manufacturing project?

Contact ProMed to learn about the range of solutions and materials we offer as well as our decades of silicone injection molding experience.

Contact Us

Advantages of Silicone Injection Molding in Medical Manufacturing

For companies seeking high-quality and cost-effective products for the medical sector, silicone injection molding is an ideal solution.  Silicone injection molding has several benefits compared to other molding processes, and the following is why this method is a great choice for medical manufacturing. To learn more about ProMed’s medical injection molding and our commitment to quality, watch our short video.

 

  • High Quality & Very Reproducible: silicone injection molding produces products that are virtually identical from part to part which provides excellent brand consistency and part reliability during high volume runs – this is especially crucial for devices used in the medical industry. High reproducibility also allows for production to be scaled up to very large volumes, resulting in low costs per unit once the upfront equipment set-up costs are paid.

 

  • Excellent Versatility: silicone injection molding is able to manufacture a wide range of part sizes, materials, and colors. Additionally, this form of molding allows for the use of multiple materials simultaneously, allowing for a high degree of customization.

 

  • Able to Produce Complex Parts: silicone injection molding is typically performed at high pressure which forces the silicone into small crevices in the mold (that other molding processes are unable to reach), enabling the production of intricate and complex parts.

 

  • Efficient Production & Low Cost Per Unit: silicone injection molding is a very fast process that quickly generates high volumes compared to other molding methods, making injection molding a more efficient and cost-effective solution. Additionally, silicone injection molding is highly automated via the use of machines and robotics, requiring less oversight by operations personnel. Automation reduces labor costs which further decreases the manufacturing costs per unit, especially for high volume production.

 

  • Low Waste Generation: silicone injection molding manufactures smooth products that have minimal finishing requirements after removal from the mold – resulting in less waste generation compared to other medical manufacturing techniques. In some cases, silicone injection molding waste is able to be reused, resulting in a more environmentally-friendly and lower cost process.

ProMed – Your Silicone Injection Molding Partner

ProMed was founded in 1989 to address an industry need for cleanroom manufacturing of silicone components, specifically those having a medical application. We have garnered a reputation as the world benchmark of implantable silicone components and assemblies – and are one of few companies in the world to provide contract manufacturing of drug-eluting products.

ProMed has expertise in working with the full spectrum of silicones covering a wide range of properties and characteristics. We will assist in your material selection to help ensure all design requirements are met. Our manufacturing facilities and equipment are designed for a single purpose—to mold medical and implantable silicone, combination components, and bio-material grade plastics with uncompromising quality and service. We currently have four divisions that are located within two manufacturing sites. All are certified class 10,000 / ISO Class 7 cleanrooms.

We can identify the right medical manufacturing solution for any project. We have extensive experience in a wide range of silicone injection molding techniques including:

  • Automated Injection Molding
  • Multi-cavity tooling
  • Micro molds and micro molding
  • Servo-controlled de-molding capabilities
  • Insert molds, overmolds, and automation integration
  • Transfer molding
  • Compression molding

 

Click here to see why ProMed is your silicone injection molding partner. Contact ProMed today at 763-331-3800 to discuss your next medical manufacturing project.


Micro-Injection Molding 101

Medical products continue to shrink in size but grow in capability as the demand increases for more portable and functional devices such as implantables, wearable devices, hearing aids, and surgical instruments. Medical manufacturers must keep up with these advancements and be able to manufacture smaller, more complex devices without sacrificing quality.

The trend toward miniaturization of medical devices has resulted in an increase in micro-injection molding, a form of manufacturing that creates tiny and often complex parts. Below is more information on this form of injection molding and why it is gaining popularity across the healthcare sector. When it comes to selecting a micro-injection molding partner, OEMs must choose wisely as this form of manufacturing requires specialized equipment and skills that many injection molding companies do not possess. The team at ProMed have the know-how and state-of-the-art equipment to successfully perform a broad range of molding methods including micro-injection molding. Our team is focused on meeting the challenges that product miniaturization often present and we are positioned to assist with all of your injection molding needs

What is Micro-Injection Molding?

Micro-injection molding is a tight tolerance method of manufacturing that produces miniscule parts – often weighing significantly less than 1 gram with dimensions measured in millimeters. Many industries benefit from these tiny products including the medical market which has numerous applications for these devices. Healthcare providers as well as patients have pushed for less invasive procedures, thus, medical devices are meeting these demands by becoming smaller with more complex features.

While there are some variations between micro-injection molding methods, the main equipment and process are generally the same. The process begins when silicone is fed into a heated barrel. In the case of Liquid Silicone Rubber (LSR), manufacturing, the two liquid LSR components are stored in separate containers and then fed simultaneously into the barrel. Next, a screw is used to mix, heat, and transport the silicone toward to the mold. The melted material is then injected through a nozzle into the mold and travels via a gate and runner system into the tiny mold cavities; the proper design of the gate and runner system is essential to ensuring the mold is filled properly. As the silicone enters the mold, excess air can be released via vents. The pressure and temperature of the mold are maintained to allow the silicone to conform to the desired shape and harden quickly. Once the part is adequately cooled, the mold opens and the part is ejected, sometimes with the help of ejector pins. The mold is then ready to receive the next shot of silicone.

Micro-injection molding is one of the latest innovations within injection molding. Due to their size, these miniature products weigh significantly less than prior versions of medical devices. This is a significant advancement for medical manufacturing as weight has historically been a challenge for the healthcare sector. Smaller and lighter parts lead to less material usage and lower cost per part – a huge win for medical manufacturing, giving OEMs a competitive advantage.

Benefits of Using LSR for Micro-Injection Moldin

Silicones have long been a popular material for medical devices and medical device components due to their durability, ease of molding by many methods, wide temperature range, chemical inertness, high tensile strength, vast range of available durometers, low toxicity, and compatibility with many sterilization methods. Furthermore, silicone is compatible with human tissue and body fluids, has a very low tissue response when implanted, and does not support bacteria growth – making it a perfect option for implants. Additionally, medical-grade silicones, such as LSR, have undergone stringent purity and biocompatibility testing that make them suitable for short and long-term usage.

LSR has a lower viscosity than many other medical-grade silicones, meaning LSR is less viscous and more readily flows. Due to its lower viscosity, LSR is a good fit for micro-injection molding as it is able to fill the tiny micro spaces in the mold. Additionally, LSR’s desirable handling properties and lower shrink rate make it an excellent choice for manufacturing complex geometries and intricate micro-sized products. Due to the automated nature of injection molding, LSR can produce high volumes of components in a short period of time.

Looking for a reliable and proven partner for your next medical manufacturing project?

Contact ProMed to learn about the range of solutions and materials we offer as well as our decades of silicone injection molding experience.

Contact Us

Challenges of Micro-Injection Molding

While the micro-injection molding process is relatively similar to standard injection molding, there are some challenges that exist due to the scale of micro parts.

Micro-injection molding demands unparalleled precision. The weight and dimensional accuracy required in micro tooling and throughout the molding process is incredible – often measured in millimeters or milligrams. Tooling required for micro-injection molding is specialized and requires extreme attention to detail to ensure consistent alignment throughout the life cycle of the mold – which is often millions of micro parts.

Material dosing is more challenging when working with micro amounts. LSR is a 2-part liquid that cures into a solid form when mixed, which are often referred to as the A and B components. For micro-injection molding, feeding the precise dosage and ratio of A and B components of LSR is crucial to ensure the desired product quality and properties. Additionally, if additives, such as a color, are added the dosage must remain precise in order to achieve consistency from batch to batch.

Micro-injection molding requires a small shot of silicone material. Due to the small volume of material, operating conditions such as pressure and temperature throughout the molding process must be uniform and balanced to ensure proper filling and distribution of the material.

Due to their tiny size and weight, micro parts must be handled more carefully than standard injection molded products. Micro parts are often more fragile and susceptible to damage during handling and assembly. LSR parts are often tacky, further complicating the automated as well as manual handling process for micro parts. In addition, ensuring a thorough and comprehensive inspection of the miniature parts is often a challenge for micro molders.

In order to have a successful project, OEMs must partner with a micro-molder, like ProMed, that has the requisite experience with the equipment, materials, and potential pitfalls of micro-injection molding. Even the slightest deviation during micro-molding will result in parts that are unusable. OEMs must leverage the experience of their micro partner, especially during the part design and prototyping stages where many key decisions are made that will significantly impact the success of the final product.

What OEMs Should Look for in a Micro-Injection Molding Partner?

It is imperative that OEMs understand that not all injection molding companies are equipped for micro-injection molding. OEMs must look for certain characteristics when selecting a micro-molding partner such as quality control, state-of-the-art equipment, and tooling experience. At ProMed, we offer customers a broad range of silicone material and equipment offerings, including micro-injection molding, which enables us to provide support as your business grows over time.

Manufacturers that perform micro-injection molding must have ample experience and expertise with micro-molding equipment. Equipment that is able to manufacture small parts via injection molding is not necessarily able to create micro parts. As noted above, micro-molding operates at very tight tolerances and very small masses – requiring exacting and repeatability that is often not feasible with standard injection molding equipment. OEMs need a manufacturer, like ProMed, that has the necessary know-how and state-of-the-art tooling and equipment to successfully manufacture micro parts.

Similar to injection molding, OEMs must ensure micro-injection molding companies meet the requisite regulations and quality standards for the healthcare sector. Clean rooms are one method that medical manufacturers use to meet these requirements. At ProMed, our manufacturing facilities are equipped with certified class 10,000 / ISO Class 7 clean rooms, demonstrating our strong commitment to quality.

About ProMed

ProMed was founded in 1989 to address an industry need for cleanroom manufacturing of silicone components, specifically those having a medical application. Over time, we broadened our product offerings to include assembly, micro-molding of highly engineered plastics, and combination products. We have garnered a reputation as the world benchmark of implantable silicone components and assemblies – and are one of few companies in the world to provide contract manufacturing of drug-eluting products.

ProMed has expertise in working with the full spectrum of silicones covering a wide range of properties and characteristics. We will assist in your material selection to help ensure all design requirements are met. Our manufacturing facilities and equipment are designed for a single purpose—to mold medical and implantable silicone, combination components, and bio-material grade plastics with uncompromising quality and service. We currently have four divisions that are located within two manufacturing sites. All are certified class 10,000 / ISO Class 7 cleanrooms.

We can identify the right manufacturing solution for any project. We have extensive experience in a wide range of injection molding techniques including:

· Automated Injection Molding

· Multi-cavity tooling

· Micro molds and micro molding

· Servo-controlled de-molding capabilities

· Insert molds, overmolds, and automation integration

· Transfer molding

· Compression molding

 

Click here to see why ProMed is your silicone injection molding partner. Contact ProMed today at 763-331-3800 to discuss your next silicone injection molding project


5 Benefits of Complete Prototyping Services in Medical Manufacturing

When it comes to molding, the initial tooling cost can be pricey and time-consuming. Thus, companies often utilize rapid prototyping to fine-tune the design and work out any potential manufacturability issues prior to investing in the tooling that will be utilized for final production. The advantages of prototyping are extensive, and below are 5 benefits of rapid prototyping services in medical manufacturing.

It should be noted that some injection molding manufacturers focus on high volume production runs, and often do not give much attention to prototyping. That is not ProMed’s approach. The ProMed team offers cost effective solutions for rapid prototyping, and does not shy away from low volume production for medical manufacturing. Regardless of the volume, ProMed views each project as an opportunity to build a long-term relationship with a customer. Watch our short video to learn more about our complete prototyping services.

  1. Optimizes Design: rapid prototyping enables the design to be optimized by early identification of design flaws or manufacturing issues. Simply put, this step ensures products can be manufactured cost-effectively and at high quality well before final production. During rapid prototyping, the team has the opportunity to address unforeseen design challenges and test product features and manufacturing methods before initiating full-scale production.
  2. Enables Quick Reiterations: rapid prototyping is an iterative process that allows designers to incorporate valuable feedback from customers and end-users into the final design. This step improves the design as well as creating a higher level of customer satisfaction in the final product. With each iteration, confidence in the final design and the product’s marketability grows.
  3. Ensures Quicker Speed to Market: any time saved during product development directly corresponds to faster speed to market. OEMs are often in a rush to get a new product to market so it is tempting to shorten – or even skip – the prototyping step. However, it is important to keep in mind that changes to the design become exponentially more expensive and timely to implement as the product advances through the life-cycle.

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Contact ProMed to learn more about our prototyping services and our range of silicone molding solutions.

  1. Lowers Manufacturing Risk: there is some degree of risk associated with every manufacturing project and rapid prototyping lowers the risk level. Prototypes enable designers to quickly discard ideas that will not result in a successful manufacturing project – and focus on the designs that will. A thorough Design for Manufacturing process (DFM) upfront allows optimizations to be made or issues to be resolved before the changes significantly impact the project timeline and budget – reducing the project risk.
  2. Reduces Cost:  tooling for injection molds is often expensive to fabricate and costly to modify; thus, it is imperative to get the tool design right the first time. If the design is off even by a small margin, the product aesthetics and functionality will be altered. Rapid prototyping gets the tool design right and ensures product manufacturability. These steps result in higher quality production, less rework, and lower waste generation – leading to significantly lower costs.

ProMed Prototyping Expertise

ProMed Prototypes fills a market void by offering customers real molded parts, made from a wide variety of materials. Our team of rapid prototyping experts offers complete in-house mold design, mold build, and prototype component manufacturing. Allowing ProMed to serve its customers throughout a product’s lifecycle decreases production development time, development cost, and production piece part price due to critical manufacturing information learned through prototyping. Click here for a comparison of the speed, cost, and likeness to production for different prototype materials.

ProMed Prototypes offers rapid prototypes that include tool design, tool manufacturing, prototype manufacturing, cleaning, packaging, and shipment. ProMed provides customers a distinct advantage because, in the world of product development, time is money, and getting a product to market before the competition is a key to the success of the long-term business strategy. When your device is ready for full scale production, ProMed Prototypes’ manufacturing knowledge will be transferred to the New Product Development department of ProMed Molded Products for pre-production runs, validation, and ongoing production runs. We focus on prototypes for the following industries:

  • Medical: Dedicated quality system, facilities and personnel support the activities necessary to develop and manufacture these drug eluting components. Working with both established and early-stage medical device and pharmaceutical companies, we develop robust manufacturing processes and platforms for the controlled release of drugs from a variety of materials. Our medical prototypes are offered in a variety of materials including LSR, HCR, and RTV.
  • Aerospace and Defense: ProMed also has more than ten years of experience in serving the aerospace and defense markets. We offer rapid prototypes of nearly any geometry and material type, along with complex assembly and over-molding prototypes for the aerospace market. ProMed Prototypes has leveraged its experience to become a leader in providing precision rapid prototypes to the aerospace and defense markets, along with ProMed Molded Products taking many aerospace and defense products into full production.
  • Pharmaceuticals: ProMed Pharma, offers rapid prototypes for drug eluting and drug delivery components, among other pharmaceutical, medical device, and combination products. ProMed Pharma focuses on silicone and plastic pharmaceutical prototypes but has extensive experience in final product assembly and packaging as well.

Contact ProMed

 

Contact ProMed today at 763-331-3800 to discuss your next prototype.

 


Medical-Grade Liquid Silicone Rubber

The Value of DFM (Design for Manufacturing)

Design for Manufacturing, or DFM, is the process of designing products for ease of manufacturing as well as creating a better, more cost-effective product. DFM is a vital product-development step that looks to simplify and optimize the design to ensure high quality and efficiency during production.

Successful silicone molded parts must be designed from the beginning to be manufacturable. The DFM process should occur early in the design phase of any injection molding project and should engage key parties including designers, tool fabricators, raw material suppliers, manufacturers, and other stakeholders. The goal is to tap into the experience of each of these experts. The team will scrutinize the current design from many angles with the goal of identifying a more cost-effective solution that maintains quality!

Part design should be focused on the ease of manufacturing because it can help reduce cost and lead to a robust and reliable process. Several aspects of the design will be considered during the DFM process: part geometry, location and shape of critical surfaces, size, and among others. Additionally, the DFM process should consider material selection, dimensioning/tolerancing, and the selection of critical dimensions as all of these factors impact manufacturability. By making the right material, color, durometer, dimension, and tolerance choices, OEMs can develop molded devices and components that can be reliably manufactured in large volume—while minimizing scrap rates and losses.

The Value of DFM

OEMs need to ensure the part is as easy to manufacture as possible! This will result in more efficient production, better quality, and lower cycle times. Below are some ways OEMs gain value from the Design for Manufacturing process.

  • Save Significant Cost and Time: OEMs are often in a rush to get a new product to market so it is tempting to shorten – or even skip – the DFM process. However, it is important to keep in mind that changes to the design become exponentially more expensive and timely to implement as the product advances through the life-cycle. A thorough DFM upfront will allow any optimizations to be made or issues to be resolved before the changes significantly impact the project timeline or budget! When it comes to DFM, the old adage “an ounce of prevention is worth a pound of cure” is very true!
  • Optimize Functionality and Aesthetics: tooling for injection molds is often expensive to fabricate and costly to modify; thus, it is imperative to get the tool design right the first time! If the design is off even by a small margin, the product aesthetics and functionality will be altered. The DFM process typically includes computer simulations of the design so the team can fully visualize the product. Oftentimes, this step yields additional insights and optimizations that would have been lost if the DFM process was not performed – resulting in a more functional and aesthetically-pleasing product.
  • Confirm Manufacturability: last but certainly not least, the DFM process ensures the part can be manufactured! This may seem obvious but there are more instances of products reaching production only to realize the product cannot actually be manufactured per its current design – what a nightmare! To avoid this situation, OEMS should partner with an experienced injection molder, like ProMed, that has DFM expertise. ProMed’s design and manufacturing teams are integrated to allow manufacturability issues to be identified and addressed during the design process instead of after the tooling is fabricated – saving customers significant development time and cost as well as innumerable headaches! ProMed works with customers throughout the product life-cycle, providing a cost-effective solution that meets the customer’s needs!

ProMed’s DFM Approach

Over the years, ProMed has evolved into a full-service provider of molded parts and assembled products, including molded silicone components, biomaterial grade plastic components, combination components (pharmaceuticals into silicone) and value-added assemblies. We have garnered a reputation as the world benchmark of implantable silicone components and assemblies – and are one of few companies in the world to provide contract manufacturing of drug-eluting products. Through multiple media platforms, ProMed’s collaborative DFM meetings include a diverse group of engineering experience that work to provide you with the best path that will meet your requirements, budget and timeline.

Our innovative processes range from simply molding components to automated assembly to providing complete devices. We utilize state-of-the art technology, draw from an experienced technical community, and take a creative systematic approach to provide you with a dependable, high-quality and overall cost-effective solution to your manufacturing needs. Let our team of experts take you all the way from concept to completion – or jump in anywhere in between. We offer complete in-house production and technical services such as:

  • Design, tooling, molding and assembly
  • Transfer, liquid injection, RTV, insert and compression molding capabilities
  • Standardized tooling platforms
  • IQ/OQ/PQ activities

Contact ProMed today at 763-331-3800 to discuss how we can help with your next silicone injection molding project!


Liquid Silicone Rubber vs High Consistency Rubber for Medical Device Components

Silicone elastomers have long been a popular material for medical devices and medical device components due to their durability, ease of molding by many methods, wide temperature range, chemical inertness, high tensile strength, vast range of available durometers, low toxicity, and compatibility with many sterilization methods. Furthermore, silicone is compatible with human tissue and body fluids, has a very low tissue response when implanted, and does not support bacteria growth – making it a perfect option for implants due to its excellent biocompatibility.

Silicone elastomers are available in two commercial forms: Liquid Silicone Rubber (LSR) and High Consistency Rubber (HCR). HCR is known for its gummy consistency and mostly comes in partially vulcanized sheets. LSR is a newer technology and starts out as a 2-part liquid that cures into a solid form when mixed. LSR generally comes in buckets and has a longer shelf life than HCR.

Medical device OEMs often face a tough decision: should we use HCR or LSR for our medical device component manufacturing? LSR and HCR are both used to manufacture medical device products; however, there are some key differences. The following compares LSR and HCR to shed some light on their differences and when each should be utilized.

Viscosity Difference Leads to Different LSR and HCR Manufacturing Techniques

The performance characteristics of HCR and LSR are relatively similar; however, viscosity is a key differentiator between LSR and HCR, and has a significant impact on the equipment and processes used to manufacture each of these elastomers.

Simply put, viscosity is a measure of a material’s ability to flow. A low viscosity indicates a material is less viscous and more readily flows where a high viscosity indicates a material is more viscous and less apt to flow well. For reference, water has a relatively low viscosity and easily flows whereas molasses has a higher viscosity and is more resistant to flow.

LSR has a lower viscosity than HCR. Due to the lower viscosity, LSR is most often processed via injection molding. LSR’s desirable handling properties and lower shrink rate make it an excellent choice for manufacturing highly complex geometries and intricate products. Additionally, due to the automated nature of injection molding, LSR can produce high volumes of components in a short period of time. For this reason, deciding whether HCR or LSR injection molding is the better choice for your project largely depends on the production volume required.

A lower viscosity makes it easier for manufacturers to mix additives into LSR. Additives that can readily be incorporated into a batch of LSR include colorants, desiccants, barium, and pharmaceuticals such as hormones or steroids. For these reasons, LSR is a great option for medical devices such as combination products. The low viscosity of LSR and the temperatures needed to vulcanize LSR are usually low enough that significant degradation of compounded substances, like Active Pharmaceutical Ingredients (APIs) that are used in combination products, can be avoided.

Due to its higher viscosity and more challenging handling properties, HCR is typically processed using compression and transfer molding methods, which are more labor-intensive. In some cases, HCR is used in injection molding projects.

OEMs Often Prefer LSR

For companies already using HCR to manufacture medical device components, it may make sense to continue using this elastomer especially since the initial capital equipment costs have already been made. For new product development, however, LSR is often the best choice given the lower capital costs and labor associated with processing this elastomer. Due to its lower manufacturing cost and versatility with formulations, companies often prefer LSR over HCR – but the decision is on a case-by-case basis.

ProMed’s Silicone Manufacturing Capabilities

At ProMed, we combine industry-leading medical-grade LSR and HCR expertise with the latest developments in silicone materials and technology. We have garnered a reputation as the world benchmark of implantable silicone components and assemblies. From helping OEMs incorporate the latest medical-grade silicone formulations into their designs to delivering rapid silicone prototypes, we serve as a premier silicone molding contract manufacturer for medical device OEMs.

ProMed has expertise in working with the full spectrum of silicones covering a wide range of properties and characteristics. Our wide range of materials include: Liquid Silicone Rubber (LSR) 5 to 80 Durometer, High-consistency Rubber (HCR): 20 to 80 Durometer, Room Temperature Vulcanizing silicone (RTV). We will assist in your material selection to help ensure all design requirements are met.

Our manufacturing facilities and equipment are designed for a single purpose—to mold medical and implantable silicone, combination components, and bio-material grade plastics with uncompromising quality and service. We currently have four divisions that are located within two manufacturing sites. All are certified class 10,000 / ISO Class 7 cleanrooms.

Contact ProMed today at 763-331-3800 to discuss your next medical device project.


Liquid Silicone Rubber

2019 & Beyond - What the LSR Material Market is Predicting

What is LSR?

Liquid Silicone Rubber (LSR) is aplatinum-cured elastomer that can be injected into a mold cavity to manufacture a part. LSR starts out as a 2-part liquid that cures into a solid form when mixed together. LSR is a versatile rubber in the elastomer industry and has a wide range of end-uses from medical devices to consumer goods to electronics to automotive. For example, LSR can be found in catheters, stents, windshield wiper blades, LED headlights, adhesives, microwaves, seals, and grommets.

There are several types of LSR that can be manufactured such as medical, self-lubricating, conductive, flame-retardant, and radio opaque. The type of LSR produced is determined by the additives incorporated during the manufacturing process. Additionally, LSR is available in different grades, namely medical, food, and industrial.

LSR has many attractive properties such as durability, low viscosity, chemical and temperature resistance, and flexibility, but its biocompatibility is outstanding. LSR has demonstrated superb compatibility with human tissue and body fluids, and is resistant to bacteria growth. Medical grades of LSR are temperature resistance and can easily sterilize, which makes them compatible with various medical devices and accessories such as implantable devices, liquid feeding bottles, dialysis filters, and oxygen mask instruments.

LSR MarketPredictions through 2026

The LSR market is forecasted to steadily grow over the next 5-10 years and some sources estimate the global market for LSR will reach a valuation of US$ 7.9 billion by 2026. Additionally, the global LSR market is forecasted to have a Compound Annual Growth Rate, or CAGR, of 4.5% through 2026 which is considered moderate growth. (Note: CAGR is considered a good measure of an investment’s return over time compared to annual return figures that do not account for compounding).

This growth is attributed to several factors. First, enhancements to the physical properties of LSR is expected to allow LSR to continue to replace traditional rubber materials in various applications. Additionally, injection molding of LSR produces consistent parts, cycle to cycle, and is a low-cost option for part manufacturing; for these reasons, LSR injection molding continues to expand into new markets, driving the continued demand for LSR.

LSR growth is also attributed to several societal factors such as growing demand for LSR in equipment and surgical tools necessary to treat the rising geriatric population and the growing awareness about health concerns, accelerated demand within the electronics industry due to continued innovation and technology advancements, as well as global urbanization and standard of living increases.  The industries that are expected to demonstrate the highest demand for LSR are medical and automotive.

Among the various grades of LSR, medical grade is expected to continue to hold the largest global market share. Moreover, stricter regulations and compliances of many specifications for use in medical products are further projected to drive the overall market growth. In addition, replacement of latex with LSR in impactable devices is expected to provide new opportunities for LSR applications.

The LSR market is segmented across five regions: Asia Pacific, North America, Europe, Latin America, and the Middle East & Africa (MEA). Among these, Asia Pacific is expected to continue as the largest marketplace for LSR, estimated at 35% of global market share, due to demand for the product in electrical & electronics and medical applications. Other factors contributing to the market growth are the easy access to raw material and favorable government policies. China and India are the strongest country-based markets in the Asia-Pacific region since distribution networks are well established and many LSR players have a strong presence in these countries.

The North America market, the United States in particular, is also forecasted to grow due to increasing usage of LSR in the electronics industry as well asincreased expenditures on, and technological advances of, medical devices. Europe is also forecasted to grow LSR demand due to growing demand for lightweight material in the automobile sector. Additionally, multinational companies are focusing on collaboration,and perhaps even joint ventures, with distributors to achieve sustainable growth. The Latin America and MEA regions are also expected to observe LSR market growth due to increasing demand for growing usage of LSR in consumer goods and healthcare industries.

The LSR market faces a couple key challenges including minimization of the carbon footprint associated with LSR production, and improvement of LSR’s reusability and disposability. But even with these challenges, the LSR market is forecasted to have moderate growth across all 5 regions as LSR usage expands to even more markets.

Contact ProMed today at 763-331-3800 to find a solution to your medical molding needs.


ProMed Pharma Mobile

The Importance of Medical-Grade Liquid Silicone Rubber

Medical-grade Liquid Silicone Rubber (LSR) is becoming increasingly crucial to the medical device industry, as the combination of the general benefits of medical-grade silicones combine with LSR’s unique advantages for medical device OEMs. As new medical-grade LSR materials become commercially available, more reliable, better performing, and more affordable medical devices will be within reach of patients.

Medical-Grade Silicones

Silicone has long been a popular material for medical device manufacturers due to its durability, ease of molding by many methods, wide useful temperature range, chemical inertness, high tensile strength, vast range of available durometers, biocompatibility, and compatibility with many sterilization methods.

Medical-grade silicones add the benefits of stringent purity and biocompatibility testing, making them suitable for use in long-term implants.

One application where medical-grade silicones really shine is drug-eluting implantable devices. Before molding, silicones can be compounded with active pharmaceutical ingredients (APIs) such as cancer drugs or hormones which can can then be steadily released into a targeted area of the patient’s body over time once that molded implant is inserted.

Drug-eluting implants are able to maintain the desired level of the API in the patient much more consistently and over a longer period of time than both pills and injections. Also, since the implant can usually be inserted near the targeted organ or tissue, lower total amounts of API are needed because that API doesn’t need to spread throughout the entire body before reaching the targeted area.

As a result, the level of the API in the patient’s body remains inside the therapeutic window (the range of concentrations between too low to be effective and high enough to be toxic) for a much longer duration.

As we’ll see shortly, medical-grade LSR is a great material for making drug-eluting implants, due to its processing advantages.

The Advantages of LSR

LSR is a type of silicone material which starts out as two separate liquid components which are then precisely mixed together before injection into a heated mold, where the silicone elastomer becomes solid (i.e. vulcanizes).

The low viscosity of LSR makes it a great silicone material for making parts via injection molding, since the LSR can easily flow into and completely fill molds with relatively low injection pressures, even those with intricate and small features.

LSR’s inherent compatibility with injection molding results in the cost-effective, repeatable, and scalable manufacture of silicone parts—including medical devices and their components.

Furthermore, the temperatures needed to vulcanize LSR are usually low enough that significant degradation of compounded substances like APIs can be avoided. Thus, medical-grade LSR an excellent material for drug-eluting implants.

Implantables aren’t the only medical device application suitable for medical-grade LSR. Wearables (such as heart rate and activity monitors), respiratory products, linings for prosthetic limbs, and other devices which must stay in prolonged physical contact with a patient all benefit from medical-grade LSR’s outstanding biocompatibility and purity.

The Future of Medical-Grade LSRs

New and improved medical devices originate from innovations in both design and materials. As new medical-grade LSRs continue to be released on the market, the medical device industry as a whole will make steady advances and improve the length and quality of life of patients around the world.

Dow Corning’s release earlier this year of two new LSRs is a prime example. These new LSR materials cure quickly at low temperatures, don’t require a primer for binding to many substrates (including polyester), need low injection pressures, and boast broad process windows.

These are all significant features for the medical device industry for the following reasons:

  • Fast cure times at low vulcanizing temperatures enable silicone injection molders to shorten the total molding cycle time (which in turn can greatly reduce the cost per molded part), and consume less energy for each silicone part since the mold will not need to heated as much as other LSRs may require. Both of these result in reduce production costs for medical-grade LSR products, and consequently, lower costs for the patients and insurance companies to purchase these products.
  • The lower injection pressures of these LSRs will allow silicone medical device manufacturers to utilize more economical, lower tonnage injection presses. These LSRs’ broad process windows can enable lower defect and scrap rates, due to a more forgiving molding process.

New medical-grade LSRs, like these from Dow Corning, will help the whole medical device supply chain ramp up production capacity to meet global demand.

At ProMed, we combine industry-leading medical-grade LSR expertise with the latest developments in silicone materials and technology. From helping OEMs incorporate the latest medical-grade LSR formulations into their designs to delivering rapid silicone prototypes, we serve as a premier silicone molding contract manufacturer for medical device OEMs. Contact us to find out how we can help you.